Charles Wood, Ph.D., Founder and Director of NCV
“The story of the Nebraska Center for Virology is really about donors. Donors made this happen.”
Charles Wood, Ph.D., is a UNL biology and biochemistry professor and NCV researcher who holds the Lewis Lehr/3M University Professorship. He helped found the NCV in 2000, bringing together scientists from Creighton University and the University of Nebraska Medical Center to study viruses in humans, plants and animals.
The NCV story begins with UNL alumnus and businessman Lewis “Lew” Lehr. In 1986, Lehr had endowed a chair in molecular genetics and biology, hoping to attract a top-notch scientist to the University of Nebraska. It worked. In 1996, Wood came to UNL, in part because the fund supported by Lehr through the University of Nebraska Foundation would enable him to take the first steps toward starting the NCV and also to continue his work fighting HIV in Africa.
“I came here with the goal of building a program that Lew had envisioned, focused on human genetics, more biomedical,” Wood said. “I was able to use the initial support to recruit a couple of researchers in virology, expanding and supporting the work that I do.”
The fellowship money enabled Wood to lay the groundwork for a strong research program, which then meant he was able to successfully apply for a $10 million grant from the National Institutes of Health. The NCV was off to a great start, but Wood knew it needed a building of its own. He wanted to bring together the UNL scientists who were scattered all over campus in different buildings because they were affiliated with different departments.
Another donor stepped forward to make that happen. Thanks to Hastings, Nebraska, businessman Ken Morrison (1921-2015), the NCV brought together all of the UNL scientists in 2008 in the new Ken Morrison Life Sciences Research Center, which was expanded in 2014.
“We were able to build a cluster strength in plant, animal and human virus research and to build a very strong training environment for the next generation of researchers and scientists,” said Wood. “We are known as one of the strongest virology programs in the country.”
The NCV’s projects are varied and include everything from plant defensive systems to viruses that attack swine, cows and other animals. One lab has developed a vaccine for porcine reproductive and respiratory syndrome virus which has been licensed to a pharmaceutical company for commercialization. Another team is studying a smallpox-like virus and how it evades the host’s immune system. Human diseases under the microscope at NCV include HIV, herpes, many strains of influenza, human cancer viruses like the papillomavirus that causes cervical cancer, and emerging diseases such as Zika.
“The environment is wonderful for the research,” Wood said of the Ken Morrison Life Sciences Research Center. “And I think that plays a big part in our successes.”